| IA: Cedar Rapids-Waterloo-Dubuque (Iowa Direct TV) | | 2 | KGAN | Programs on CBS include: Ghost Whisperer, Miami Trauma, The Early Show, People's Choice Awards, NFL on CBS/The NFL Today, NCIS, PGA Tour Golf, Sun Bowl, and Cold Case. | Local |
| 7 | KWWL | Programs on NBC include: Kentucky Derby, The NHL, Heroes, VeggieTales, Parks and Recreation, Babar, Dragon, Jacob Two-Two, and Community. | Local |
| 9 | KCRG | Programs on ABC include: British Open, Supernanny, Cougar Town, This Week, Brothers & Sisters, NBA on ABC, Wife Swap, Scrubs, and Private Practice. | Local |
| 12 | KIIN | Programs on PBS include: DragonflyTV, Curious George, The Woodwright's Shop, Ask This Old House, Baking With Julia, Design e2, Dinosaur Train, GED Connection, and Washington Week. | Local |
| 20 | KWKB | Programs on CW include: Supernatural, The Tyra Banks Show, Smallville, The Vampire Diaries, Gossip Girl, Life Unexpected, Melrose Place, America's Next Top Model, and 90210. | Local |
| 28 | KFXA | Programs on FOX include: Teen Choice Awards, Glee, Lie to Me, NAACP Image Awards, House, Fox News Sunday, So You Think You Can Dance, Bones, and Past Life. | Local |
| IA: Des Moines-Ames (Iowa Direct TV) | | 5 | WOI | Programs on ABC include: British Open, Supernanny, Cougar Town, This Week, Brothers & Sisters, NBA on ABC, Wife Swap, Scrubs, and Private Practice. | Local |
| 8 | KCCI | Programs on CBS include: Ghost Whisperer, Miami Trauma, The Early Show, People's Choice Awards, NFL on CBS/The NFL Today, NCIS, PGA Tour Golf, Sun Bowl, and Cold Case. | Local |
| 11 | KDIN | Programs on PBS include: DragonflyTV, Curious George, The Woodwright's Shop, Ask This Old House, Baking With Julia, Design e2, Dinosaur Train, GED Connection, and Washington Week. | Local |
| 13 | WHO | Programs on NBC include: Kentucky Derby, The NHL, Heroes, VeggieTales, Parks and Recreation, Babar, Dragon, Jacob Two-Two, and Community. | Local |
| 17 | KDSM | Programs on FOX include: Teen Choice Awards, Glee, Lie to Me, NAACP Image Awards, House, Fox News Sunday, So You Think You Can Dance, Bones, and Past Life. | Local |
| 23 | KCWI | Programs on CW include: Supernatural, The Tyra Banks Show, Smallville, The Vampire Diaries, Gossip Girl, Life Unexpected, Melrose Place, America's Next Top Model, and 90210. | Local |
| IA: Rapid City (Iowa Direct TV) |
| IA: Sioux City (Iowa Direct TV) |
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