| MS: Columbus-Tupelo-West Point (Mississippi Satellite TV) | | 4 | 4 | WCBI | Programs on CBS include: 60 Minutes, Let's Make a Deal, The Bold and the Beautiful, CSI: Crime Scene Investigation, The Young and the Restless, 48 Hours, Rules of Engagement, Big Brother, and Medium. | Local | Local |
| 9 | 9 | WTVA | Programs on NBC include: Law & Order: Special Victims Unit, The Olympics through 2012, Friday Night Lights, French Open Tennis, Meet the Press, The NHL, Dragon, PGA Tour Golf, and 3-2-1 Penguins!/Larry Boy Stories. | Local | Local |
| 12 | 2 | WMAE | Programs on PBS include: Austin City Limits, Secrets of the Dead, Everyday Food, WordGirl, Baking With Julia, Motorweek, It's a Big Big World, Independent Lens, and Dragon Tales. | Local | Local |
| 27 | 27 | WLOV | Programs on FOX include: New Year's Eve Live, Kitchen Nightmares, NASCAR on Fox, NFL on Fox/Fox NFL Sunday, Hell's Kitchen, Bowl Championship Series, Glee, Major League Baseball on Fox, and House. | Local | Local |
| 45 | 45 | WKDH | Programs on ABC include: 20/20, Jimmy Kimmel Live!, Good Morning America, The Suite Life of Zack and Cody, America This Morning, Castle, Country Music Association Awards, British Open, and Scrubs. | Local | Local |
| MS: Jackson (Mississippi Satellite TV) | | 3 | 3 | WLBT | Programs on NBC include: Law & Order: Special Victims Unit, The Olympics through 2012, Friday Night Lights, French Open Tennis, Meet the Press, The NHL, Dragon, PGA Tour Golf, and 3-2-1 Penguins!/Larry Boy Stories. | Local | Local |
| 12 | 12 | WJTV | Programs on CBS include: 60 Minutes, Let's Make a Deal, The Bold and the Beautiful, CSI: Crime Scene Investigation, The Young and the Restless, 48 Hours, Rules of Engagement, Big Brother, and Medium. | Local | Local |
| 16 | 16 | WAPT | Programs on ABC include: 20/20, Jimmy Kimmel Live!, Good Morning America, The Suite Life of Zack and Cody, America This Morning, Castle, Country Music Association Awards, British Open, and Scrubs. | Local | Local |
| 29 | 29 | WMPN | Programs on PBS include: Austin City Limits, Secrets of the Dead, Everyday Food, WordGirl, Baking With Julia, Motorweek, It's a Big Big World, Independent Lens, and Dragon Tales. | Local | Local |
| 34 | 34 | WRBJ | Programs on CW include: 90210, Life Unexpected, One Tree Hill, The Vampire Diaries, Melrose Place, Gossip Girl, Smallville, Supernatural, and The Tyra Banks Show. | Local | Local |
| 35 | 35 | WUFX | WUFX (MNT) | Local | Local |
| 40 | 40 | WDBD | Programs on FOX include: New Year's Eve Live, Kitchen Nightmares, NASCAR on Fox, NFL on Fox/Fox NFL Sunday, Hell's Kitchen, Bowl Championship Series, Glee, Major League Baseball on Fox, and House. | Local | Local |
| MS: Meridian (Mississippi Satellite TV) | | - | 11 | WTOK | Programs on ABC include: 20/20, Jimmy Kimmel Live!, Good Morning America, The Suite Life of Zack and Cody, America This Morning, Castle, Country Music Association Awards, British Open, and Scrubs. | - | Local |
| - | 24 | WMDN | Programs on CBS include: 60 Minutes, Let's Make a Deal, The Bold and the Beautiful, CSI: Crime Scene Investigation, The Young and the Restless, 48 Hours, Rules of Engagement, Big Brother, and Medium. | - | Local |
| - | 29 | WMAW | Programs on PBS include: Austin City Limits, Secrets of the Dead, Everyday Food, WordGirl, Baking With Julia, Motorweek, It's a Big Big World, Independent Lens, and Dragon Tales. | - | Local |
| - | 30 | WGBC | Programs on NBC include: Law & Order: Special Victims Unit, The Olympics through 2012, Friday Night Lights, French Open Tennis, Meet the Press, The NHL, Dragon, PGA Tour Golf, and 3-2-1 Penguins!/Larry Boy Stories. | - | Local |
| - | 49 | WTOKD | Programs on FOX include: New Year's Eve Live, Kitchen Nightmares, NASCAR on Fox, NFL on Fox/Fox NFL Sunday, Hell's Kitchen, Bowl Championship Series, Glee, Major League Baseball on Fox, and House. | - | Local |
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