| Local Channels (Greenville Satellite TV) | | 2 | 2 | WDTN | Programs on NBC include: The Jay Leno Show, VeggieTales, NBC Nightly News, Law & Order: Special Victims Unit, Early Today, Last Call with Carson Daly, The Tonight Show with Conan O'Brien, The Biggest Loser, and The NHL. | Local | Local |
| 7 | 7 | WHIO | Programs on CBS include: Academy of Country Music Awards, Numb3rs, Southeastern Conference Football, Busytown Mysteries, How I Met Your Mother, The Early Show, Arranged Marriage, Cold Case, and NCAA Basketball. | Local | Local |
| 16 | 16 | WPTD | Programs on PBS include: The Woodwright's Shop, Mister Rogers' Neighborhood, Nature, DragonflyTV, P.O.V., Antiques Roadshow, NOVA scienceNOW, Masterpiece, and FETCH! with Ruff Ruffman. | Local | Local |
| 22 | 22 | WKEF | Programs on ABC include: Supernanny, The View, Belmont Stakes, American Music Awards, The Bachelorette, Ugly Betty, World News Now, Better Off Ted, and Modern Family. | Local | Local |
| 26 | 26 | WBDT | Programs on CW include: 90210, Life Unexpected, Melrose Place, Gossip Girl, The Tyra Banks Show, America's Next Top Model, One Tree Hill, The Vampire Diaries, and Smallville. | Local | Local |
| 45 | 45 | WRGT | Programs on FOX include: NASCAR on Fox, Major League Baseball on Fox, The Cleveland Show, Bones, COPS, NAACP Image Awards, So You Think You Can Dance, The Simpsons, and NFL on Fox/Fox NFL Sunday. | Local | Local |
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