| SC: Charleston (South Carolina Satellite TV) | | 2 | 2 | WCBD | Programs on NBC include: 3-2-1 Penguins!/Larry Boy Stories, The Tonight Show with Conan O'Brien, Today, Law & Order, The Biggest Loser, Miss USA, Law & Order: Criminal Intent, Friday Night Lights, and French Open Tennis. | Local | Local |
| 4 | 4 | WCIV | Programs on ABC include: The Replacements, Belmont Stakes, Saturday Night College Football, The Bachelorette, World News Now, This Week, Cougar Town, Major League Soccer, and General Hospital. | Local | Local |
| 5 | 5 | WCSC | Programs on CBS include: Southeastern Conference Football, CSI: NY, The Early Show, US Open Tennis, Sun Bowl, The Late Late Show with Craig Ferguson, NCIS, Busytown Mysteries, and The Big Bang Theory. | Local | Local |
| 7 | - | ETV | Programs on PBS include: American Experience, Super Why!, Clifford the Big Red Dog, Design Squad, The Electric Company, Dragon Tales, Austin City Limits, Soundstage, and NOVA. | Local | - |
| - | 7 | WITV | Programs on PBS include: American Experience, Super Why!, Clifford the Big Red Dog, Design Squad, The Electric Company, Dragon Tales, Austin City Limits, Soundstage, and NOVA. | - | Local |
| 14 | - | CW | Programs on CW include: Smallville, America's Next Top Model, The Vampire Diaries, Melrose Place, The Tyra Banks Show, 90210, Supernatural, Gossip Girl, and One Tree Hill. | Local | - |
| 24 | 24 | WTAT | Programs on FOX include: The Simpsons, Fox News Sunday, Sons of Tucson, The Cleveland Show, Major League Baseball on Fox, So You Think You Can Dance, Bones, Family Guy, and House. | Local | Local |
| 36 | 36 | WMMP | WMMP (MNT) | Local | Local |
| SC: Columbia (South Carolina Satellite TV) | | 10 | 10 | WIS | Programs on NBC include: 3-2-1 Penguins!/Larry Boy Stories, The Tonight Show with Conan O'Brien, Today, Law & Order, The Biggest Loser, Miss USA, Law & Order: Criminal Intent, Friday Night Lights, and French Open Tennis. | Local | Local |
| 19 | 19 | WLTX | Programs on CBS include: Southeastern Conference Football, CSI: NY, The Early Show, US Open Tennis, Sun Bowl, The Late Late Show with Craig Ferguson, NCIS, Busytown Mysteries, and The Big Bang Theory. | Local | Local |
| 25 | 25 | WOLO | Programs on ABC include: The Replacements, Belmont Stakes, Saturday Night College Football, The Bachelorette, World News Now, This Week, Cougar Town, Major League Soccer, and General Hospital. | Local | Local |
| 35 | 35 | WRLK | Programs on PBS include: American Experience, Super Why!, Clifford the Big Red Dog, Design Squad, The Electric Company, Dragon Tales, Austin City Limits, Soundstage, and NOVA. | Local | Local |
| 47 | 47 | WZRB | Programs on CW include: Smallville, America's Next Top Model, The Vampire Diaries, Melrose Place, The Tyra Banks Show, 90210, Supernatural, Gossip Girl, and One Tree Hill. | Local | Local |
| 57 | 57 | WACH | Programs on FOX include: The Simpsons, Fox News Sunday, Sons of Tucson, The Cleveland Show, Major League Baseball on Fox, So You Think You Can Dance, Bones, Family Guy, and House. | Local | Local |
| 63 | 63 | WKTC | WKTC (MNT) | Local | Local |
| SC: Florence-Myrtle Beach (South Carolina Satellite TV) | | 10 | - | WIS | Programs on NBC include: 3-2-1 Penguins!/Larry Boy Stories, The Tonight Show with Conan O'Brien, Today, Law & Order, The Biggest Loser, Miss USA, Law & Order: Criminal Intent, Friday Night Lights, and French Open Tennis. | Local | - |
| 13 | 13 | WBTW | Programs on CBS include: Southeastern Conference Football, CSI: NY, The Early Show, US Open Tennis, Sun Bowl, The Late Late Show with Craig Ferguson, NCIS, Busytown Mysteries, and The Big Bang Theory. | Local | Local |
| 15 | 15 | WPDE | Programs on ABC include: The Replacements, Belmont Stakes, Saturday Night College Football, The Bachelorette, World News Now, This Week, Cougar Town, Major League Soccer, and General Hospital. | Local | Local |
| 21 | 21 | WWMB | Programs on CW include: Smallville, America's Next Top Model, The Vampire Diaries, Melrose Place, The Tyra Banks Show, 90210, Supernatural, Gossip Girl, and One Tree Hill. | Local | Local |
| 31 | - | UNC | Programs on PBS include: American Experience, Super Why!, Clifford the Big Red Dog, Design Squad, The Electric Company, Dragon Tales, Austin City Limits, Soundstage, and NOVA. | Local | - |
| - | 31 | WUNU | Programs on PBS include: American Experience, Super Why!, Clifford the Big Red Dog, Design Squad, The Electric Company, Dragon Tales, Austin City Limits, Soundstage, and NOVA. | - | Local |
| 33 | - | ETV | Programs on PBS include: American Experience, Super Why!, Clifford the Big Red Dog, Design Squad, The Electric Company, Dragon Tales, Austin City Limits, Soundstage, and NOVA. | Local | - |
| - | 33 | WJPM | Programs on PBS include: American Experience, Super Why!, Clifford the Big Red Dog, Design Squad, The Electric Company, Dragon Tales, Austin City Limits, Soundstage, and NOVA. | - | Local |
| 43 | 43 | WFXB | Programs on FOX include: The Simpsons, Fox News Sunday, Sons of Tucson, The Cleveland Show, Major League Baseball on Fox, So You Think You Can Dance, Bones, Family Guy, and House. | Local | Local |
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